General mail failure. Quit Microsoft Excel, restart the mail system, and try again.

General mail failure. Quit Microsoft Excel, restart the mail system, and try again.

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General mail failure. Quit Microsoft Excel, restart the mail system, and try again.

How to fix General mail failure. Quit Microsoft Excel, restart the mail system, and try again.

When a user tries to share a spreadsheet as an attachment by email in Microsoft Excel then he may receive the error: General mail failure. Quit Microsoft Excel, restart the mail system, and try again.
General mail failure. Quit Microsoft Excel, restart the mail system, and try again.” prompts because the email client is unable to handle the request due to incorrectly installed, missing/corrupted files or multiple office versions are installed.

Error Message

General mail failure. Quit Microsoft Excel, restart the mail system, and try again.

You might want to read about Either there is no default mail client or the current mail client cannot fulfill the messaging request.

Causes of General mail failure. Quit Microsoft Excel, restart the mail system, and try again.

Below mentioned are the various potential triggers that can cause General mail failure. Quit Microsoft Excel, restart the mail system, and try again.

  • Unable to identify the default email client
  • Add ons or Extensions causing the issue
  • Another version of Outlook already exists.
  • Corrupt Office installation

Resolution of General mail failure. Quit Microsoft Excel, restart the mail system, and try again.

We have made a list of resolutions which we can try to fix the Error “General mail failure. Quit Microsoft Excel, restart the mail system, and try again”. We have listed the solutions to resolve the error.
Performing the below-mentioned solutions and workaround help us to resolve the error “General mail failure. Quit Microsoft Excel, restart the mail system, and try again”.

  • Set Default Email Client
  • Messaging Application Program Interface (MSMapi) File Updation
  • Disable Add-ins
  • Increase the Outlook Attachment Size Limit
  • Repair Office installation
  • Remove other Office Versions

1. Set Outlook As Default Email Client

  • Go to Start and click on Control Panel or Press Windows+R keys to open the Run box. Type “control” into the “Open” field, and then hit Enter or click on Ok to launch Control Panel
  • Choose Default Programs from the Control panel.
  • Click on Set your Default programs option.
  • Select Microsoft Outlook from the drop-down menu.
  • Click on Set this program as default to set Outlook as a default mail application.

If Microsoft Outlook is already a default email client, then there is some other reason causing the error General mail failure. Quit Microsoft Excel, restart the mail system, and try again.

Set Outlook As Default Email Client

2. Messaging Application Program Interface (MSMapi) File Updation

MSMAPI files are used to describe message services and their service providers and forms. If it used by another program or service then it may cause the error “General mail failure. Quit Microsoft Excel, restart the mail system, and try again.”

  • Navigate to C:\Program Files\Common Files\System\MSMAPI\<LocaleID>
    • (LocaleID is 1033 for English versions)
  • Locate and Rename MSMAPI32.dll to MSMAPI32.old.

Now check if the issue still exists.

MSMAPI32.dll

3. Disable Third Party Add-ins

Starting Outlook in Safe Mode can let you safely use it while it has encountered problems. This is helpful when you can’t open a file in normal mode because the application is crashing or there is an extension or add-in causing a problem on startup.

In safe mode, the Outllok may not open with the options provided by addins but can perform basic operations.

  • Find the shortcut icon of Outlook.
  • Press and hold the CTRL key and double-click the Outlook icon shortcut.
  • Click Yes on the prompt to start the application in Safe Mode. Or Press Windows+R keys to open the Run box. Type “outlook/safe” into the “Open” field, and then hit Enter or click on Ok to launch Outlook in Safe mode.
  • Once Outlook is open click on File > Manage Add-ins.
  • Under Manage add-ins, in the Turned on column, uncheck the box for the add-in you want to turn off.

If Outlook fails to open in Safe Mode, you may be required to reinstall the application from a reliable resource.

Manage Add-ins Outlook
COM Add-ins

4. Increase Outlook Attachment Size Limit

If you are attempting to send an email with attachment more than 20MB, then you also might get the error “General mail failure. Quit Microsoft Excel, restart the mail system, and try again.”. By default, Outlook does not send emails with attachments that exceed 20 MB, but many mail servers allow 25 MB or larger attachments. If your email server allows larger attachments, configure Outlook to send emails larger than 20 MB.

  • Press Windows Key + R to open Run command, type regedit in the open field, and click Ok.
  • Navigate the registry tree and go to the entry corresponding to your Outlook version:
    • Outlook 2019 and 2016HKEY_CURRENT_USER\­Software\­Microsoft\­Office\­16.0\­Outlook\­Preferences
    • Outlook 2013HKEY_CURRENT_USER\­Software\­Microsoft\­Office\­15.0\­Outlook\Preferences
    • Outlook 2010HKEY_CURRENT_USER\­Software\­Microsoft\­Office\­14.0\­Outlook\Preferences
  • Double-click the MaximumAttachmentSize value.
    • Note: If you don’t see MaximumAttachmentSize, add a registry key and value. Go to Edit, select New > DWORD Value, enter MaximumAttachmentSize, and press Enter.
  • In the Value data text box, enter the desired attachment size in KB(KiloByte).
  • Select OK and Close the Registry Editor.
regedit
MaximumAttachmentSize

5. Repair Office installation

If you have start receiving the error message “General mail failure. Quit Microsoft Excel, restart the mail system, and try again.” after the installation of an Office application, try to fix the problem by repairing the Office installation.

  • Go to Start and click on Control Panel.
  • From Category view, under Programs, click on Uninstall a program. or Press Windows+R keys to open the Run box. Type “appwiz.cpl” into the “Open” field, and then hit Enter or click on Ok to launch Programs and Features.
  • Select the Office product you want to repair, and then click Change.
  • Depending if your copy of Office is Click-to-run or an MSI-based install, do the following for your Office installation type:
    • Click-to-Run installation type: In How would you like to repair your Office Programs, select Quick Repair to detect and replace corrupted files and then select Repair.
    • MSI-based installation type: In Change your installation, select Repair and then click Continue.
  • Follow the remaining instructions on the screen to complete the repair.
Repair Office installation

6. Remove Other Office Versions

Multiple Office installation can also cause “General mail failure. Quit Microsoft Excel, restart the mail system, and try again.”. Consider removing Microsoft Office versions installed from the device and check again.

Uninstall Office from the Control Panel

  • Press Windows Key + R to open Run command, type appwiz.cpl and click Ok. Or Open Control Panel –>Programs
  • Right-click on the Microsoft Office product, and choose Uninstall.
  • Follow the instructions on the screen.

Uninstall Office using Microsoft Easy Fix Tool

Try running Microsoft Easy Fix tool to completely remove Office from the device.

Reference: Microsoft Article for uninstalling Office
Consider installing office after restarting the device.

Frequently Asked Questions

  1. What is a General email failure error?

    General mail failure error prompts when the email client is unable to handle the request due to incorrectly installed, missing, or corrupted files.
  2. How to set the default email client?

    Click on Start > Control Panel. Select Default Programs from the Control panel. Click on Set your Default programs option. Select the Mail client that you want to set as default from the drop-down menu
  3. Can you have different versions of Office installed?

    Microsoft does not recommend installing multiple versions of Office products, but it is possible to install and use more than one version of Office on a single Windows computer. For example, you can install and use both Office 2016 and Office 2010 on the same computer.

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